Nascent RNA scaffolds contribute to chromosome territory architecture and counter chromatin compaction.

Creamer, Kevin Michael; Kolpa, Heather Jill; Lawrence, Jeanne Bentley

Creamer, Kevin Michael; Kolpa, Heather Jill; Lawrence, Jeanne Bentley.

Affiliation

Creamer KM; Department of Neurology and Pediatrics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Kolpa HJ; Department of Neurology and Pediatrics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.
Lawrence JB; Department of Neurology and Pediatrics, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA. Electronic address: jeanne.lawrence@umassmed.edu.

Mol Cell ; 81(17): 3509-3525.e5, 2021 09 02.

Article in En | MEDLINE | ID: mdl-34320406

Subject(s)

Chromatin/metabolism; Nuclear Matrix/metabolism; RNA, Untranslated/metabolism; Animals; Cell Line; Cell Nucleus/physiology; Chromatin/genetics; Chromosomes/genetics; Chromosomes/metabolism; Euchromatin/metabolism; Humans; Mice; Nuclear Matrix/genetics; RNA/genetics; RNA/metabolism; RNA, Long Noncoding/genetics; RNA, Untranslated/genetics; Transcription, Genetic/genetics

Key words

HNRNPU; NUMA; SAF-A; XIST; chromatin-associated RNA; nascent RNA; nuclear matrix; nuclear scaffold; nucleus; scaffold-attachment regions

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Nuclear Matrix / RNA, Untranslated Limits: Animals / Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United States

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