A composite DNA element that functions as a maintainer required for epigenetic inheritance of heterochromatin.

Wang, Xiaoyi; Paulo, Joao A; Li, Xue; Zhou, Haining; Yu, Juntao; Gygi, Steven P; Moazed, Danesh

Wang, Xiaoyi; Paulo, Joao A; Li, Xue; Zhou, Haining; Yu, Juntao; Gygi, Steven P; Moazed, Danesh.

Affiliation

Wang X; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Paulo JA; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Li X; Bioinformatics and Integrative Biology Program, University of Massachusetts Medical School, Worcester, MA, USA.
Zhou H; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Yu J; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Gygi SP; Department of Cell Biology, Harvard Medical School, Boston, MA, USA.
Moazed D; Howard Hughes Medical Institute, Department of Cell Biology, Harvard Medical School, Boston, MA, USA. Electronic address: danesh@hms.harvard.edu.

Mol Cell ; 81(19): 3979-3991.e4, 2021 10 07.

Article in En | MEDLINE | ID: mdl-34375584

Subject(s)

Chromatin Assembly and Disassembly; DNA Methylation; DNA, Fungal/genetics; Heredity; Heterochromatin/genetics; Regulatory Sequences, Nucleic Acid; Schizosaccharomyces/genetics; Activating Transcription Factors/genetics; Activating Transcription Factors/metabolism; Adenosine Triphosphatases/genetics; Adenosine Triphosphatases/metabolism; Binding Sites; Cell Cycle Proteins/genetics; Cell Cycle Proteins/metabolism; DNA, Fungal/metabolism; Epigenesis, Genetic; Gene Expression Regulation, Fungal; Heterochromatin/metabolism; Histone-Lysine N-Methyltransferase/genetics; Histone-Lysine N-Methyltransferase/metabolism; Histones/genetics; Histones/metabolism; Origin Recognition Complex/genetics; Origin Recognition Complex/metabolism; Proteins/genetics; Proteins/metabolism; RNA Interference; Schizosaccharomyces/metabolism; Schizosaccharomyces pombe Proteins/genetics; Schizosaccharomyces pombe Proteins/metabolism

Key words

Atf1; Clr4; Deb1; H3K9me; ORC; Pcr1; Suv39h; epigenetic inheritance; heterochromatin; maintainer

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Schizosaccharomyces / DNA, Fungal / Heterochromatin / Regulatory Sequences, Nucleic Acid / DNA Methylation / Heredity / Chromatin Assembly and Disassembly Type of study: Prognostic_studies Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2021 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google