Parallel pathways for recruiting effector proteins determine centromere drive and suppression.

Kumon, Tomohiro; Ma, Jun; Akins, R Brian; Stefanik, Derek; Nordgren, C Erik; Kim, Junhyong; Levine, Mia T; Lampson, Michael A

Kumon, Tomohiro; Ma, Jun; Akins, R Brian; Stefanik, Derek; Nordgren, C Erik; Kim, Junhyong; Levine, Mia T; Lampson, Michael A.

Affiliation

Kumon T; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ma J; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Akins RB; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Stefanik D; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Nordgren CE; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Kim J; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA.
Levine MT; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA; Epigenetics Institute, University of Pennsylvania, Philadelphia, PA 19104, USA.
Lampson MA; Department of Biology, School of Arts and Sciences, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: lampson@sas.upenn.edu.

Cell ; 184(19): 4904-4918.e11, 2021 09 16.

Article in En | MEDLINE | ID: mdl-34433012

Subject(s)

Centromere Protein B/metabolism; Centromere/metabolism; Chromosomal Proteins, Non-Histone/metabolism; Alleles; Amino Acid Sequence; Animals; Biological Evolution; CRISPR-Cas Systems/genetics; Centromere Protein A/metabolism; Chromosomal Proteins, Non-Histone/chemistry; Chromosomes, Mammalian/metabolism; Female; Heterochromatin/metabolism; Kinetochores/metabolism; Male; Mice, Inbred C57BL; Models, Biological; Oocytes/metabolism; Protein Domains

Key words

centromere; evolutionary arms race; heterochromatin; kinetochore; meiotic drive; selfish genetic elements

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomal Proteins, Non-Histone / Centromere / Centromere Protein B Limits: Animals Language: En Journal: Cell Year: 2021 Type: Article Affiliation country: United States

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