Positive predictive value of sustained virologic response 4 weeks posttreatment for achieving sustained virologic response 12 weeks posttreatment in patients receiving glecaprevir/pibrentasvir in Phase 2 and 3 clinical trials.

Gane, Edward; de Ledinghen, Victor; Dylla, Douglas E; Rizzardini, Giuliano; Shiffman, Mitchell L; Barclay, Stephen T; Calleja, Jose Luis; Xue, Zhenyi; Burroughs, Margaret; Gutierrez, Julio A

Positive predictive value of sustained virologic response 4 weeks posttreatment for achieving sustained virologic response 12 weeks posttreatment in patients receiving glecaprevir/pibrentasvir in Phase 2 and 3 clinical trials.

Gane, Edward; de Ledinghen, Victor; Dylla, Douglas E; Rizzardini, Giuliano; Shiffman, Mitchell L; Barclay, Stephen T; Calleja, Jose Luis; Xue, Zhenyi; Burroughs, Margaret; Gutierrez, Julio A.

Affiliation

Gane E; Faculty of Medicine, University of Auckland, Auckland, New Zealand.
de Ledinghen V; Centre d'Investigation de la Fibrose Hépatique, Bordeaux University Hospital, Pessac, France.
Dylla DE; INSERM U1053, Bordeaux University, Bordeaux, France.
Rizzardini G; AbbVie Inc, North Chicago, Illinois, USA.
Shiffman ML; 1st Division of Infectious Diseases, ASST Fatebenefratelli-Sacco, Milan, Italy.
Barclay ST; Liver Institute of Virginia, Bon Secours Mercy Health, Richmond, Virginia, USA.
Calleja JL; Department of Gastroenterology, Glasgow Royal Infirmary, Glasgow, UK.
Xue Z; Department of Gastroenterology and Hepatology, Hospital Universitario Puerta de Hierro, Madrid, Spain.
Burroughs M; AbbVie Inc, North Chicago, Illinois, USA.
Gutierrez JA; AbbVie Inc, North Chicago, Illinois, USA.

J Viral Hepat ; 28(11): 1635-1642, 2021 11.

Article in En | MEDLINE | ID: mdl-34448313

Subject(s)

Antiviral Agents; Hepatitis C, Chronic; Aminoisobutyric Acids; Antiviral Agents/therapeutic use; Benzimidazoles; Cyclopropanes; Genotype; Hepacivirus/genetics; Hepatitis C, Chronic/drug therapy; Humans; Lactams, Macrocyclic; Leucine/analogs & derivatives; Predictive Value of Tests; Proline/analogs & derivatives; Pyrrolidines; Quinoxalines/therapeutic use; Sulfonamides; Sustained Virologic Response; Treatment Outcome

Key words

care cascade; concordance; direct-acting antivirals; hepatitis C virus; sustained virologic response

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Hepatitis C, Chronic Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: J Viral Hepat Journal subject: GASTROENTEROLOGIA Year: 2021 Type: Article Affiliation country: New Zealand

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