In vitro efficacy of Artemisia extracts against SARS-CoV-2.
Virol J
; 18(1): 182, 2021 09 08.
Article
in En
| MEDLINE
| ID: mdl-34496903
ABSTRACT
BACKGROUND:
Traditional medicines based on herbal extracts have been proposed as affordable treatments for patients suffering from coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Teas and drinks containing extracts of Artemisia annua and Artemisia afra have been widely used in Africa in efforts to prevent SARS-CoV-2 infection and fight COVID-19.METHODS:
The plant extracts and Covid-Organics drink produced in Madagascar were tested for plaque reduction using both feline coronavirus and SARS-CoV-2 in vitro. Their cytotoxicities were also investigated.RESULTS:
Several extracts as well as Covid-Organics inhibited SARS-CoV-2 and FCoV infection at concentrations that did not affect cell viability.CONCLUSIONS:
Some plant extracts show inhibitory activity against FCoV and SARS-CoV-2. However, it remains unclear whether peak plasma concentrations in humans can reach levels needed to inhibit viral infection following consumption of teas or Covid-Organics. Clinical studies are required to evaluate the utility of these drinks for COVID-19 prevention or treatment of patients.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Plant Extracts
/
Artemisia
/
SARS-CoV-2
Limits:
Animals
Language:
En
Journal:
Virol J
Journal subject:
VIROLOGIA
Year:
2021
Type:
Article
Affiliation country:
Germany