Remodelin, a N-acetyltransferase 10 (NAT10) inhibitor, alters mitochondrial lipid metabolism in cancer cells.

Dalhat, Mahmood Hassan; Mohammed, Mohammed Razeeth Shait; Ahmad, Abrar; Khan, Mohammad Imran; Choudhry, Hani

Dalhat, Mahmood Hassan; Mohammed, Mohammed Razeeth Shait; Ahmad, Abrar; Khan, Mohammad Imran; Choudhry, Hani.

Affiliation

Dalhat MH; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Mohammed MRS; Centre for Artificial Intelligence in Precision Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Ahmad A; Cancer and Mutagenesis Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia.
Khan MI; Department of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia.
Choudhry H; Centre for Artificial Intelligence in Precision Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

J Cell Biochem ; 122(12): 1936-1945, 2021 12.

Article in En | MEDLINE | ID: mdl-34605570

Subject(s)

Hydrazones/pharmacology; Lipid Metabolism/drug effects; Mitochondria/metabolism; N-Terminal Acetyltransferases/antagonists & inhibitors; Neoplasm Proteins/antagonists & inhibitors; Neoplasms/metabolism; Thiazoles/pharmacology; HCT116 Cells; Humans; MCF-7 Cells; N-Terminal Acetyltransferases/metabolism; Neoplasm Proteins/metabolism; Neoplasms/drug therapy

Key words

NAT10; cancer; metabolomics; remodelin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiazoles / Lipid Metabolism / N-Terminal Acetyltransferases / Hydrazones / Mitochondria / Neoplasm Proteins / Neoplasms Limits: Humans Language: En Journal: J Cell Biochem Year: 2021 Type: Article Affiliation country: Saudi Arabia

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