Your browser doesn't support javascript.
loading
SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma.
Wilke, Anne C; Doebele, Carmen; Zindel, Alena; Lee, Kwang Seok; Rieke, Sara A; Ceribelli, Michele; Comoglio, Federico; Phelan, James D; Wang, James Q; Pikman, Yana; Jahn, Dominique; Häupl, Björn; Schneider, Constanze; Scheich, Sebastian; Tosto, Frances A; Bohnenberger, Hanibal; Stauder, Philipp; Schnütgen, Frank; Slabicki, Mikolaj; Coulibaly, Zana A; Wolf, Sebastian; Bojarczuk, Kamil; Chapuy, Björn; Brandts, Christian H; Stroebel, Philipp; Lewis, Caroline A; Engelke, Michael; Xu, Xincheng; Kim, Hahn; Dang, Thanh Hung; Schmitz, Roland; Hodson, Daniel J; Stegmaier, Kimberly; Urlaub, Henning; Serve, Hubert; Schmitt, Clemens A; Kreuz, Fernando; Knittel, Gero; Rabinowitz, Joshua D; Reinhardt, Hans Christian; Vander Heiden, Matthew G; Thomas, Craig; Staudt, Louis M; Zenz, Thorsten; Oellerich, Thomas.
Affiliation
  • Wilke AC; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Doebele C; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Zindel A; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Lee KS; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Rieke SA; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Ceribelli M; Molecular Therapy in Haematology and Oncology and Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany.
  • Comoglio F; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Phelan JD; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Rockville, MD.
  • Wang JQ; enGene Statistics GmbH, Basel, Switzerland.
  • Pikman Y; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Jahn D; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Häupl B; Division of Hematology/Oncology, Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA.
  • Schneider C; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Scheich S; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Tosto FA; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Bohnenberger H; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Stauder P; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Schnütgen F; Division of Hematology/Oncology, Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA.
  • Slabicki M; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt, Germany.
  • Coulibaly ZA; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Wolf S; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Bojarczuk K; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, Rockville, MD.
  • Chapuy B; Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany.
  • Brandts CH; Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany.
  • Stroebel P; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Lewis CA; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Engelke M; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt, Germany.
  • Xu X; Molecular Therapy in Haematology and Oncology and Department of Translational Oncology, NCT and DKFZ, Heidelberg, Germany.
  • Kim H; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Dang TH; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Schmitz R; Department of Hematology and Oncology, Georg August University, Göttingen, Germany.
  • Hodson DJ; Department of Experimental Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Stegmaier K; Department of Hematology and Oncology, Georg August University, Göttingen, Germany.
  • Urlaub H; Department of Medicine II, Department for Hematology/Oncology, Goethe University, Frankfurt, Germany.
  • Serve H; German Cancer Research Center and German Cancer Consortium, Heidelberg, Germany.
  • Schmitt CA; Frankfurt Cancer Institute, Goethe University Frankfurt, Frankfurt, Germany.
  • Kreuz F; Institute of Pathology, University Medical Center Göttingen, Göttingen, Germany.
  • Knittel G; Whitehead Institute for Biomedical Research, Cambridge, MA.
  • Rabinowitz JD; Institute of Cellular and Molecular Immunology, Georg August University of Göttingen, Göttingen, Germany.
  • Reinhardt HC; Lewis-Sigler Institute for Integrative Genomics.
  • Vander Heiden MG; Department of Chemistry, and.
  • Thomas C; Department of Chemistry, and.
  • Staudt LM; Princeton University Small Molecule Screening Center, Princeton University, Princeton, NJ.
  • Zenz T; Institute for Pathology, Molecular Cytology and Functional Genomics, University Hospital Giessen, Giessen, Germany.
  • Oellerich T; Institute for Pathology, Molecular Cytology and Functional Genomics, University Hospital Giessen, Giessen, Germany.
Blood ; 139(4): 538-553, 2022 01 27.
Article in En | MEDLINE | ID: mdl-34624079

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycine Hydroxymethyltransferase / Burkitt Lymphoma / Basic Helix-Loop-Helix Transcription Factors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2022 Type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glycine Hydroxymethyltransferase / Burkitt Lymphoma / Basic Helix-Loop-Helix Transcription Factors Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2022 Type: Article Affiliation country: Germany