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Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling.
Loser, Dominik; Grillberger, Karin; Hinojosa, Maria G; Blum, Jonathan; Haufe, Yves; Danker, Timm; Johansson, Ylva; Möller, Clemens; Nicke, Annette; Bennekou, Susanne H; Gardner, Iain; Bauch, Caroline; Walker, Paul; Forsby, Anna; Ecker, Gerhard F; Kraushaar, Udo; Leist, Marcel.
Affiliation
  • Loser D; NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770, Reutlingen, Germany.
  • Grillberger K; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457, Konstanz, Germany.
  • Hinojosa MG; Department of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
  • Blum J; Department of Biochemistry and Biophysics, Stockholm University, 106 91, Stockholm, Sweden.
  • Haufe Y; In Vitro Toxicology and Biomedicine, Department Inaugurated by the Doerenkamp-Zbinden Foundation, University of Konstanz, 78457, Konstanz, Germany.
  • Danker T; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, LMU Munich, 80336, Munich, Germany.
  • Johansson Y; NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770, Reutlingen, Germany.
  • Möller C; Department of Biochemistry and Biophysics, Stockholm University, 106 91, Stockholm, Sweden.
  • Nicke A; Life Sciences Faculty, Albstadt-Sigmaringen University, 72488, Sigmaringen, Germany.
  • Bennekou SH; Walther Straub Institute of Pharmacology and Toxicology, Faculty of Medicine, LMU Munich, 80336, Munich, Germany.
  • Gardner I; Technical University of Denmark, Kongens Lyngby, Denmark.
  • Bauch C; CERTARA UK Limited, Simcyp Division, Level 2-Acero, 1 Concourse Way, Sheffield, S1 2BJ, UK.
  • Walker P; Cyprotex Discovery Ltd, No. 24 Mereside, Alderley Park, Cheshire, SK10 4TG, UK.
  • Forsby A; Cyprotex Discovery Ltd, No. 24 Mereside, Alderley Park, Cheshire, SK10 4TG, UK.
  • Ecker GF; Department of Biochemistry and Biophysics, Stockholm University, 106 91, Stockholm, Sweden.
  • Kraushaar U; Department of Pharmaceutical Chemistry, University of Vienna, Vienna, Austria.
  • Leist M; NMI Natural and Medical Sciences Institute at the University of Tübingen, 72770, Reutlingen, Germany.
Arch Toxicol ; 95(12): 3695-3716, 2021 Dec.
Article in En | MEDLINE | ID: mdl-34628512
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Receptors, Nicotinic / Nicotinic Agonists / Imidazolines / Neonicotinoids / Nitro Compounds Limits: Animals / Humans Language: En Journal: Arch Toxicol Year: 2021 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Receptors, Nicotinic / Nicotinic Agonists / Imidazolines / Neonicotinoids / Nitro Compounds Limits: Animals / Humans Language: En Journal: Arch Toxicol Year: 2021 Type: Article Affiliation country: Germany