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Trained innate immunity, long-lasting epigenetic modulation, and skewed myelopoiesis by heme.
Jentho, Elisa; Ruiz-Moreno, Cristian; Novakovic, Boris; Kourtzelis, Ioannis; Megchelenbrink, Wout L; Martins, Rui; Chavakis, Triantafyllos; Soares, Miguel P; Kalafati, Lydia; Guerra, Joel; Roestel, Franziska; Bohm, Peter; Godmann, Maren; Grinenko, Tatyana; Eugster, Anne; Beretta, Martina; Joosten, Leo A B; Netea, Mihai G; Bauer, Michael; Stunnenberg, Hendrik G; Weis, Sebastian.
Affiliation
  • Jentho E; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller-University, 07747 Jena, Germany.
  • Ruiz-Moreno C; Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
  • Novakovic B; Prinses Máxima Centrum for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
  • Kourtzelis I; Science Faculty, Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, The Netherlands.
  • Megchelenbrink WL; Science Faculty, Department of Molecular Biology, Radboud University, 6525 GA Nijmegen, The Netherlands.
  • Martins R; Department of Paediatrics, Murdoch Children's Research Institute, University of Melbourne, Parkville VIC 3052, Australia.
  • Chavakis T; Institute of Clinical Chemistry and Laboratory Medicine, University Clinic Dresden, Technische Universität Dresden, 01307 Dresden, Germany.
  • Soares MP; National Center for Tumor Diseases, Partner Site Dresden, German Cancer Research Center, 69120 Heidelberg, Germany.
  • Kalafati L; Hull York Medical School, York Biomedical Research Institute, University of York, York YO10 5NG, United Kingdom.
  • Guerra J; Prinses Máxima Centrum for Pediatric Oncology, 3584 CS Utrecht, The Netherlands.
  • Roestel F; Department of Precision Medicine, University of Campania Luigi, 80138 Naples, Italy.
  • Bohm P; Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
  • Godmann M; Institute of Clinical Chemistry and Laboratory Medicine, University Clinic Dresden, Technische Universität Dresden, 01307 Dresden, Germany.
  • Grinenko T; Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal.
  • Eugster A; Institute of Clinical Chemistry and Laboratory Medicine, University Clinic Dresden, Technische Universität Dresden, 01307 Dresden, Germany.
  • Beretta M; National Center for Tumor Diseases, Partner Site Dresden, German Cancer Research Center, 69120 Heidelberg, Germany.
  • Joosten LAB; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller-University, 07747 Jena, Germany.
  • Netea MG; Center for Sepsis Control and Care, Jena University Hospital, Friedrich-Schiller-University, D-07747 Jena, Germany.
  • Bauer M; Institute for Infectious Disease and Infection Control, Jena University Hospital, Friedrich-Schiller-University, 07747 Jena, Germany.
  • Stunnenberg HG; Department of Anesthesiology and Intensive Care Medicine, Jena University Hospital, Friedrich-Schiller-University, 07747 Jena, Germany.
  • Weis S; Institute for Infectious Disease and Infection Control, Jena University Hospital, Friedrich-Schiller-University, 07747 Jena, Germany.
Proc Natl Acad Sci U S A ; 118(42)2021 10 19.
Article in En | MEDLINE | ID: mdl-34663697
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myelopoiesis / Epigenesis, Genetic / Heme / Immunity, Innate Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article Affiliation country: Germany
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myelopoiesis / Epigenesis, Genetic / Heme / Immunity, Innate Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2021 Type: Article Affiliation country: Germany