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Abatacept is useful in autoimmune cytopenia with immunopathologic manifestations caused by CTLA-4 defects.
Dhunputh, C; Ducassou, S; Fernandes, H; Picard, Capucine; Rieux-Laucat, Frédéric; Viallard, J-F; Lazaro, E; Hermine, O; Jouvray, M; Machelard, I; Lambilliotte, A; Malphettes, M; Moshous, D; Neven, B; Gauthier, A; Garnier, N; Leblanc, T; Landman-Parker, J; Leverger, G; Aladjidi, N.
Affiliation
  • Dhunputh C; Pediatric Hemato-Immunology Centre d'Investigation Clinique (CIC) 1401, INSERM Plurithématique CIC (CICP), Bordeaux University Hospital, Bordeaux, France.
  • Ducassou S; Centre de Référence National des Cytopénies Autoimmunes de l'Enfant (CEREVANCE), Bordeaux University Hospital, Bordeaux, France.
  • Fernandes H; Pediatric Hemato-Immunology Centre d'Investigation Clinique (CIC) 1401, INSERM Plurithématique CIC (CICP), Bordeaux University Hospital, Bordeaux, France.
  • Picard C; Centre de Référence National des Cytopénies Autoimmunes de l'Enfant (CEREVANCE), Bordeaux University Hospital, Bordeaux, France.
  • Rieux-Laucat F; Centre de Référence National des Cytopénies Autoimmunes de l'Enfant (CEREVANCE), Bordeaux University Hospital, Bordeaux, France.
  • Viallard JF; Study Center for Primary Immunodeficiencies, Necker Hospital for Sick Children, Assistance Publique-Hôpitaux de Paris (AP-HP), University of Paris, Paris, France.
  • Lazaro E; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, Unite Mixte de Recherche (UMR) 1163, INSERM, Paris, France.
  • Hermine O; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, Unite Mixte de Recherche (UMR) 1163, INSERM, Paris, France.
  • Jouvray M; Department of Internal Medicine and Infectious Diseases, Bordeaux University Hospital, Bordeaux, France.
  • Machelard I; Department of Internal Medicine and Infectious Diseases, Bordeaux University Hospital, Bordeaux, France.
  • Lambilliotte A; Hematology Unit, Necker-Enfants Malades University Hospital, AP-HP, Paris, France.
  • Malphettes M; Department of Internal Medicine, Hospital of Arras, Arras, France.
  • Moshous D; Department of Internal Medicine, Hospital of Bayonne, Bayonne, France.
  • Neven B; Department of Pediatric Hematology, Lille University Hospital, Lille, France.
  • Gauthier A; Clinical Immunology Department, Saint Louis University Hospital, AP-HP, Paris, France.
  • Garnier N; Pediatric Immuno-Hematology and Rheumatology Department, Necker-Enfants Malades University Hospital, AP-HP, Paris, France.
  • Leblanc T; Laboratory of Immunogenetics of Pediatric Autoimmune Diseases, Institut Imagine, Unite Mixte de Recherche (UMR) 1163, INSERM, Paris, France.
  • Landman-Parker J; Pediatric Immuno-Hematology and Rheumatology Department, Necker-Enfants Malades University Hospital, AP-HP, Paris, France.
  • Leverger G; Pediatric Hematology and Oncology Institut, Hospices Civils de Lyon, Lyon, France.
  • Aladjidi N; Laboratoire Interuniversitaire de Biologie de la Motricité, EA7424, Team Vascular Biology and Red Blood Cell, University Claude Bernard Lyon 1, University of Lyon, Lyon, France.
Blood ; 139(2): 300-304, 2022 01 13.
Article in En | MEDLINE | ID: mdl-34714911
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombocytopenia / CTLA-4 Antigen / Abatacept / Immune Checkpoint Inhibitors / Anemia, Hemolytic, Autoimmune Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: Blood Year: 2022 Type: Article Affiliation country: France
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombocytopenia / CTLA-4 Antigen / Abatacept / Immune Checkpoint Inhibitors / Anemia, Hemolytic, Autoimmune Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: Blood Year: 2022 Type: Article Affiliation country: France