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Fecal metabolomics reveals products of dysregulated proteolysis and altered microbial metabolism in obesity-related osteoarthritis.
Rushing, B R; McRitchie, S; Arbeeva, L; Nelson, A E; Azcarate-Peril, M A; Li, Y-Y; Qian, Y; Pathmasiri, W; Sumner, S C J; Loeser, R F.
Affiliation
  • Rushing BR; Department of Nutrition, University of North Carolina at Chapel Hill, Nutrition Research Institute, Kannapolis, NC, USA.
  • McRitchie S; Department of Nutrition, University of North Carolina at Chapel Hill, Nutrition Research Institute, Kannapolis, NC, USA.
  • Arbeeva L; Department of Medicine, Division of Rheumatology, Allergy and Immunology and the Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA.
  • Nelson AE; Department of Medicine, Division of Rheumatology, Allergy and Immunology and the Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA.
  • Azcarate-Peril MA; Department of Medicine, Division of Gastroenterology and Hepatology and UNC Microbiome Core, Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, NC, USA.
  • Li YY; Department of Nutrition, University of North Carolina at Chapel Hill, Nutrition Research Institute, Kannapolis, NC, USA.
  • Qian Y; Department of Nutrition, University of North Carolina at Chapel Hill, Nutrition Research Institute, Kannapolis, NC, USA.
  • Pathmasiri W; Department of Nutrition, University of North Carolina at Chapel Hill, Nutrition Research Institute, Kannapolis, NC, USA.
  • Sumner SCJ; Department of Nutrition, University of North Carolina at Chapel Hill, Nutrition Research Institute, Kannapolis, NC, USA. Electronic address: susan_sumner@unc.edu.
  • Loeser RF; Department of Medicine, Division of Rheumatology, Allergy and Immunology and the Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, USA. Electronic address: richard_loeser@med.unc.edu.
Osteoarthritis Cartilage ; 30(1): 81-91, 2022 01.
Article in En | MEDLINE | ID: mdl-34718137
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Metabolome / Feces / Proteolysis Type of study: Etiology_studies / Prognostic_studies Limits: Aged / Female / Humans / Male Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoarthritis / Metabolome / Feces / Proteolysis Type of study: Etiology_studies / Prognostic_studies Limits: Aged / Female / Humans / Male Language: En Journal: Osteoarthritis Cartilage Journal subject: ORTOPEDIA / REUMATOLOGIA Year: 2022 Type: Article Affiliation country: United States