Design of experiments and multivariate analysis approach to study dissolution stability of a modified-release drug product to support lean design strategies.

Jordan, Nika; Roskar, Robert; Grabnar, Iztok

Jordan, Nika; Roskar, Robert; Grabnar, Iztok.

Affiliation

Jordan N; Lek Pharmaceuticals d.d., Ljubljana, Slovenia.
Roskar R; University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.
Grabnar I; University of Ljubljana, Faculty of Pharmacy, Ljubljana, Slovenia.

Drug Dev Ind Pharm ; 47(9): 1481-1488, 2021 Sep.

Article in En | MEDLINE | ID: mdl-34726551

Subject(s)

Drug Packaging; Drug Stability; Linear Models; Multivariate Analysis; Solubility

Key words

Design of experiments; dissolution profile; lean stability; modified-release; multiple linear regression; prediction; stability studies

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Packaging Type of study: Prognostic_studies Language: En Journal: Drug Dev Ind Pharm Year: 2021 Type: Article Affiliation country: Slovenia

Fulltext

XML

PubMed Links

Search on Google