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SNX10-mediated LPS sensing causes intestinal barrier dysfunction via a caspase-5-dependent signaling cascade.
Wang, Xu; Ni, Jiahui; You, Yan; Feng, Guize; Zhang, Sulin; Bao, Weilian; Hou, Hui; Li, Haidong; Liu, Lixin; Zheng, Mingyue; Wang, Yirui; Zhou, Hua; Shen, Weixing; Shen, Xiaoyan.
Affiliation
  • Wang X; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Ni J; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • You Y; The First Clinical Medical College of Nanjing University of Chinese Medicine, Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China.
  • Feng G; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Zhang S; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Bao W; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Hou H; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Li H; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Liu L; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Zheng M; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Wang Y; Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.
  • Zhou H; Department of Pharmacology & the Key Laboratory of Smart Drug Delivery, Ministry of Education, School of Pharmacy, Fudan University, Shanghai, China.
  • Shen W; Faculty of Chinese Medicine and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macao, China.
  • Shen X; The First Clinical Medical College of Nanjing University of Chinese Medicine, Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine Prevention and Treatment of Tumor, Nanjing, China.
EMBO J ; 40(24): e108080, 2021 12 15.
Article in En | MEDLINE | ID: mdl-34747049
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lipopolysaccharides / Colitis / Caspases / Sorting Nexins / Bacterial Outer Membrane Type of study: Etiology_studies Limits: Animals / Female / Humans / Male Language: En Journal: EMBO J Year: 2021 Type: Article Affiliation country: China
Fulltext
Print
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lipopolysaccharides / Colitis / Caspases / Sorting Nexins / Bacterial Outer Membrane Type of study: Etiology_studies Limits: Animals / Female / Humans / Male Language: En Journal: EMBO J Year: 2021 Type: Article Affiliation country: China