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High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control.
Dreyfuss, Jonathan M; Yuchi, Yixing; Dong, Xuehong; Efthymiou, Vissarion; Pan, Hui; Simonson, Donald C; Vernon, Ashley; Halperin, Florencia; Aryal, Pratik; Konkar, Anish; Sebastian, Yinong; Higgs, Brandon W; Grimsby, Joseph; Rondinone, Cristina M; Kasif, Simon; Kahn, Barbara B; Foster, Kathleen; Seeley, Randy; Goldfine, Allison; Djordjilovic, Vera; Patti, Mary Elizabeth.
Affiliation
  • Dreyfuss JM; Bioinformatics and Biostatistics Core, Research Division, Joslin Diabetes Center, Boston, MA, USA.
  • Yuchi Y; Biomedical Engineering, Boston University, Boston, MA, USA.
  • Dong X; Harvard Medical School, Boston, MA, USA.
  • Efthymiou V; Harvard Medical School, Boston, MA, USA.
  • Pan H; Integrative Physiology and Metabolism, Research Division, Joslin Diabetes Center, Boston, MA, USA.
  • Simonson DC; Vertex Pharmaceuticals, Boston, MA, USA.
  • Vernon A; Harvard Medical School, Boston, MA, USA.
  • Halperin F; Integrative Physiology and Metabolism, Research Division, Joslin Diabetes Center, Boston, MA, USA.
  • Aryal P; Department of Endocrinology, Diabetes & Metabolism, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Konkar A; Harvard Medical School, Boston, MA, USA.
  • Sebastian Y; Integrative Physiology and Metabolism, Research Division, Joslin Diabetes Center, Boston, MA, USA.
  • Higgs BW; Bioinformatics and Biostatistics Core, Research Division, Joslin Diabetes Center, Boston, MA, USA.
  • Grimsby J; Biomedical Engineering, Boston University, Boston, MA, USA.
  • Rondinone CM; Harvard Medical School, Boston, MA, USA.
  • Kasif S; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Kahn BB; Harvard Medical School, Boston, MA, USA.
  • Foster K; Department of Surgery, Brigham and Women's Hospital, Boston, MA, USA.
  • Seeley R; Harvard Medical School, Boston, MA, USA.
  • Goldfine A; Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
  • Djordjilovic V; Form Health, Boston, MA, USA.
  • Patti ME; Harvard Medical School, Boston, MA, USA.
Nat Commun ; 12(1): 6951, 2021 11 29.
Article in En | MEDLINE | ID: mdl-34845204
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastric Bypass / Proteome / Diabetes Mellitus, Type 2 / Metabolome / Liver / Obesity Type of study: Observational_studies / Prognostic_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastric Bypass / Proteome / Diabetes Mellitus, Type 2 / Metabolome / Liver / Obesity Type of study: Observational_studies / Prognostic_studies Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: United States