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Single-cell multiomics reveals increased plasticity, resistant populations, and stem-cell-like blasts in KMT2A-rearranged leukemia.
Chen, Changya; Yu, Wenbao; Alikarami, Fatemeh; Qiu, Qi; Chen, Chia-Hui; Flournoy, Jennifer; Gao, Peng; Uzun, Yasin; Fang, Li; Davenport, James W; Hu, Yuxuan; Zhu, Qin; Wang, Kai; Libbrecht, Clara; Felmeister, Alex; Rozich, Isaiah; Ding, Yang-Yang; Hunger, Stephen P; Felix, Carolyn A; Wu, Hao; Brown, Patrick A; Guest, Erin M; Barrett, David M; Bernt, Kathrin M; Tan, Kai.
Affiliation
  • Chen C; Division of Oncology and Center for Childhood Cancer Research and.
  • Yu W; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Alikarami F; Division of Oncology and Center for Childhood Cancer Research and.
  • Qiu Q; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Chen CH; Department of Pediatrics, Perelman School of Medicine.
  • Flournoy J; Division of Oncology and Center for Childhood Cancer Research and.
  • Gao P; Department of Genetics, Perelman School of Medicine.
  • Uzun Y; Penn Epigenetics Institute, and.
  • Fang L; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA.
  • Davenport JW; Division of Oncology and Center for Childhood Cancer Research and.
  • Hu Y; Department of Genetics, Perelman School of Medicine.
  • Zhu Q; Penn Epigenetics Institute, and.
  • Wang K; Institute for Regenerative Medicine, University of Pennsylvania, Philadelphia, PA.
  • Libbrecht C; Division of Oncology and Center for Childhood Cancer Research and.
  • Felmeister A; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Rozich I; Division of Oncology and Center for Childhood Cancer Research and.
  • Ding YY; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Hunger SP; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Felix CA; Division of Oncology and Center for Childhood Cancer Research and.
  • Wu H; School of Computer Science and Technology, Xidian University, Xi'an, China.
  • Brown PA; Graduate Group in Genomics and Computational Biology.
  • Guest EM; Raymond G. Perelman Center for Cellular and Molecular Therapeutics, Children's Hospital of Philadelphia, Philadelphia, PA.
  • Barrett DM; Department of Pathology and Laboratory Medicine, and.
  • Bernt KM; Division of Oncology and Center for Childhood Cancer Research and.
  • Tan K; Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA.
Blood ; 139(14): 2198-2211, 2022 04 07.
Article in En | MEDLINE | ID: mdl-34864916
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans / Infant Language: En Journal: Blood Year: 2022 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia, Myeloid, Acute / Precursor Cell Lymphoblastic Leukemia-Lymphoma / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans / Infant Language: En Journal: Blood Year: 2022 Type: Article