Hemophagocytosis, hyper-inflammatory responses, and multiple organ damages in COVID-19-associated hyperferritinemia.

Dong, Guiying; Yu, Jianbo; Gao, Weibo; Guo, Wei; Zhu, Jihong; Wang, Tianbing

Dong, Guiying; Yu, Jianbo; Gao, Weibo; Guo, Wei; Zhu, Jihong; Wang, Tianbing.

Affiliation

Dong G; Trauma Center, Key Laboratory of Trauma and Neural Regeneration (Peking University), Ministry of Education, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, People's Republic of China.
Yu J; Emergency Department, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, People's Republic of China.
Gao W; Emergency Department, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, People's Republic of China.
Guo W; Emergency Department, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, People's Republic of China.
Zhu J; Trauma Center, Key Laboratory of Trauma and Neural Regeneration (Peking University), Ministry of Education, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, People's Republic of China.
Wang T; Emergency Department, Peking University People's Hospital, No.11 Xizhimen South Street, Beijing, 100044, People's Republic of China. zhujihong642021@163.com.

Ann Hematol ; 101(3): 513-520, 2022 Mar.

Article in En | MEDLINE | ID: mdl-34865201

Subject(s)

COVID-19/blood; Hyperferritinemia/blood; Phagocytosis; SARS-CoV-2/metabolism; Aged; C-Reactive Protein/immunology; C-Reactive Protein/metabolism; COVID-19/complications; COVID-19/mortality; Female; Fibrin Fibrinogen Degradation Products/immunology; Fibrin Fibrinogen Degradation Products/metabolism; Hospital Mortality; Humans; Hyperferritinemia/etiology; Hyperferritinemia/immunology; Hyperferritinemia/mortality; Inflammation/blood; Inflammation/immunology; Inflammation/mortality; Interleukin-6/blood; Interleukin-6/immunology; Male; Middle Aged; Prevalence; Retrospective Studies; SARS-CoV-2/immunology

Key words

COVID-19; Hemophagocytic lymphohistiocytosis; Hyperferritinemia; In-hospital mortality

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phagocytosis / Hyperferritinemia / SARS-CoV-2 / COVID-19 Type of study: Etiology_studies / Observational_studies / Prevalence_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Hematol Journal subject: HEMATOLOGIA Year: 2022 Type: Article

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