Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

Dinarello, C A; Cannon, J G; Wolff, S M; Bernheim, H A; Beutler, B; Cerami, A; Figari, I S; Palladino, M A; O'Connor, J V

Dinarello, C A; Cannon, J G; Wolff, S M; Bernheim, H A; Beutler, B; Cerami, A; Figari, I S; Palladino, M A; O'Connor, J V.

J Exp Med ; 163(6): 1433-50, 1986 Jun 01.

Article in En | MEDLINE | ID: mdl-3486936

Subject(s)

Fever/chemically induced; Glycoproteins/toxicity; Interleukin-1/biosynthesis; Pyrogens/toxicity; Animals; Dinoprostone; Endotoxins/toxicity; Glycoproteins/pharmacology; Interleukin-1/toxicity; Mice; Monocytes/drug effects; Prostaglandins E/biosynthesis; Pyrogens/pharmacology; Rabbits; Recombinant Proteins/pharmacology; Recombinant Proteins/toxicity; Stimulation, Chemical; Tumor Necrosis Factor-alpha

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrogens / Glycoproteins / Interleukin-1 / Fever Limits: Animals Language: En Journal: J Exp Med Year: 1986 Type: Article

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