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The short isoform of the host antiviral protein ZAP acts as an inhibitor of SARS-CoV-2 programmed ribosomal frameshifting.
Zimmer, Matthias M; Kibe, Anuja; Rand, Ulfert; Pekarek, Lukas; Ye, Liqing; Buck, Stefan; Smyth, Redmond P; Cicin-Sain, Luka; Caliskan, Neva.
Affiliation
  • Zimmer MM; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
  • Kibe A; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
  • Rand U; Helmholtz Zentrum für Infektionsforschung, Inhoffenstrasse 7, 38124, Braunschweig, Germany.
  • Pekarek L; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
  • Ye L; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
  • Buck S; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
  • Smyth RP; Helmholtz Institute for RNA-based Infection Research (HIRI), Helmholtz Zentrum für Infektionsforschung (Helmholtz Centre for Infection Research), Josef-Schneider-Strasse 2, 97080, Würzburg, Germany.
  • Cicin-Sain L; Medical Faculty, Julius-Maximilians University Würzburg, 97074, Würzburg, Germany.
  • Caliskan N; Helmholtz Zentrum für Infektionsforschung, Inhoffenstrasse 7, 38124, Braunschweig, Germany.
Nat Commun ; 12(1): 7193, 2021 12 10.
Article in En | MEDLINE | ID: mdl-34893599
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / RNA-Binding Proteins / Frameshifting, Ribosomal / SARS-CoV-2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Repressor Proteins / RNA-Binding Proteins / Frameshifting, Ribosomal / SARS-CoV-2 Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2021 Type: Article Affiliation country: Germany