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TET deficiency perturbs mature B cell homeostasis and promotes oncogenesis associated with accumulation of G-quadruplex and R-loop structures.
Shukla, Vipul; Samaniego-Castruita, Daniela; Dong, Zhen; González-Avalos, Edahí; Yan, Qingqing; Sarma, Kavitha; Rao, Anjana.
Affiliation
  • Shukla V; Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
  • Samaniego-Castruita D; Department of Cell and Developmental Biology, Northwestern University, Chicago, IL, USA.
  • Dong Z; Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
  • González-Avalos E; Biological Sciences Graduate Program, University of California, San Diego, La Jolla, CA, USA.
  • Yan Q; Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
  • Sarma K; Division of Signaling and Gene Expression, La Jolla Institute for Immunology, La Jolla, CA, USA.
  • Rao A; Bioinformatics and Systems Biology Graduate Program, University of California, San Diego, La Jolla, CA, USA.
Nat Immunol ; 23(1): 99-108, 2022 01.
Article in En | MEDLINE | ID: mdl-34937926

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Dioxygenases / DNA-Binding Proteins / Carcinogenesis / R-Loop Structures / Homeostasis Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Dioxygenases / DNA-Binding Proteins / Carcinogenesis / R-Loop Structures / Homeostasis Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Nat Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Type: Article Affiliation country: United States