Abatacept (Cytotoxic T Lymphocyte Antigen 4-Fragment Crystallizable) Reduces Allergic Inflammation of Ovalbumin-Sensitized Mice.

Chung, Jaein; Choi, Mi-Ra; Kim, Min Gyu; Park, Soo Kyoung; Kim, Yong Min

Chung, Jaein; Choi, Mi-Ra; Kim, Min Gyu; Park, Soo Kyoung; Kim, Yong Min.

Affiliation

Chung J; Chungnam National University School of Medicine, Daejeon, Korea.
Choi MR; Chungnam National University School of Medicine, Daejeon, Korea.
Kim MG; Chungnam National University School of Medicine, Daejeon, Korea.
Park SK; Chungnam National University School of Medicine, Daejeon, Korea.
Kim YM; Chungnam National University School of Medicine, Daejeon, Korea.

Am J Rhinol Allergy ; 36(4): 432-439, 2022 Jul.

Article in En | MEDLINE | ID: mdl-34994213

Subject(s)

Inflammation; Rhinitis, Allergic; Animals; Mice; Abatacept/therapeutic use; Abatacept/metabolism; Ovalbumin; CTLA-4 Antigen/metabolism; CTLA-4 Antigen/therapeutic use; Inflammation/metabolism; Rhinitis, Allergic/drug therapy; Rhinitis, Allergic/metabolism; Nasal Mucosa/metabolism; Cytokines/metabolism; Immunoglobulin E/metabolism; Mice, Inbred BALB C; Disease Models, Animal

Key words

BALB/c mice; CD28; CD4; CTLA4-Fc; Th2 cells; abatacept; allergy; inflammation; ovalbumin; rhinitis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhinitis, Allergic / Inflammation Limits: Animals Language: En Journal: Am J Rhinol Allergy Journal subject: ALERGIA E IMUNOLOGIA / OTORRINOLARINGOLOGIA Year: 2022 Type: Article

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