The modulation of cAMP/PKA pathway by asiaticoside ameliorates high glucose-induced inflammation and apoptosis of retinal pigment epithelial cells.

Zhang, Yixia; Meng, Xindan; Liu, Keyu

Zhang, Yixia; Meng, Xindan; Liu, Keyu.

Affiliation

Zhang Y; Department of Ophthalmology, Wanzhou aier eye hospital, Chongqing, 404100, China.
Meng X; Department of Ophthalmology, Wanzhou aier eye hospital, Chongqing, 404100, China.
Liu K; Department of Surgery, Northern Kuanren Hospital, The Second Affiliated Hospital of Chongqing Medical University, Yubei District, 69 Renhe Xingguang Avenue, Chongqing, 401120, China. liukeyu40@163.com.

J Bioenerg Biomembr ; 54(1): 9-16, 2022 02.

Article in En | MEDLINE | ID: mdl-35038080

Subject(s)

Cyclic AMP-Dependent Protein Kinases; Cyclic AMP; Apoptosis; Cyclic AMP/metabolism; Cyclic AMP/pharmacology; Cyclic AMP-Dependent Protein Kinases/metabolism; Cyclic AMP-Dependent Protein Kinases/pharmacology; Epithelial Cells/metabolism; Glucose/metabolism; Glucose/pharmacology; Humans; Inflammation/chemically induced; Inflammation/drug therapy; Inflammation/metabolism; Retinal Pigments/metabolism; Retinal Pigments/pharmacology; Triterpenes

Key words

Asiaticoside; PKA; cAMP; diabetic retinopathy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cyclic AMP-Dependent Protein Kinases / Cyclic AMP Limits: Humans Language: En Journal: J Bioenerg Biomembr Year: 2022 Type: Article Affiliation country: China

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