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Loss of TDP-43 function and rimmed vacuoles persist after T cell depletion in a xenograft model of sporadic inclusion body myositis.
Britson, Kyla A; Ling, Jonathan P; Braunstein, Kerstin E; Montagne, Janelle M; Kastenschmidt, Jenna M; Wilson, Andrew; Ikenaga, Chiseko; Tsao, William; Pinal-Fernandez, Iago; Russell, Katelyn A; Reed, Nicole; Mozaffar, Tahseen; Wagner, Kathryn R; Ostrow, Lyle W; Corse, Andrea M; Mammen, Andrew L; Villalta, S Armando; Larman, H Benjamin; Wong, Philip C; Lloyd, Thomas E.
Affiliation
  • Britson KA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Ling JP; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Braunstein KE; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Montagne JM; Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Kastenschmidt JM; Department of Physiology and Biophysics, Institute for Immunology, University of California Irvine, Irvine, CA 92697, USA.
  • Wilson A; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Ikenaga C; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Tsao W; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Pinal-Fernandez I; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Russell KA; Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Reed N; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Mozaffar T; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Wagner KR; Institute for Immunology, Department of Neurology, University of California Irvine, Irvine, CA 92697, USA.
  • Ostrow LW; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Corse AM; Center for Genetic Muscle Disorders, Kennedy Krieger Institute, Baltimore, MD 21205, USA.
  • Mammen AL; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Villalta SA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Larman HB; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
  • Wong PC; Muscle Disease Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
  • Lloyd TE; Department of Physiology and Biophysics, Institute for Immunology, University of California Irvine, Irvine, CA 92697, USA.
Sci Transl Med ; 14(628): eabi9196, 2022 01 19.
Article in En | MEDLINE | ID: mdl-35044790
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myositis, Inclusion Body / DNA-Binding Proteins / Myositis Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2022 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myositis, Inclusion Body / DNA-Binding Proteins / Myositis Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Transl Med Journal subject: CIENCIA / MEDICINA Year: 2022 Type: Article Affiliation country: United States