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Loss of glucose 6-phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells.
Aurora, Arin B; Khivansara, Vishal; Leach, Ashley; Gill, Jennifer G; Martin-Sandoval, Misty; Yang, Chendong; Kasitinon, Stacy Y; Bezwada, Divya; Tasdogan, Alpaslan; Gu, Wen; Mathews, Thomas P; Zhao, Zhiyu; DeBerardinis, Ralph J; Morrison, Sean J.
Affiliation
  • Aurora AB; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390; arin.aurora@utsouthwestern.edu sean.morrison@utsouthwestern.edu.
  • Khivansara V; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Leach A; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Gill JG; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Martin-Sandoval M; Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Yang C; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Kasitinon SY; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Bezwada D; Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Tasdogan A; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Gu W; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Mathews TP; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Zhao Z; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • DeBerardinis RJ; Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, TX 75390.
  • Morrison SJ; Children's Research Institute and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX 75390.
Proc Natl Acad Sci U S A ; 119(6)2022 02 08.
Article in En | MEDLINE | ID: mdl-35110412
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Glucosephosphate Dehydrogenase / Glutamine / Melanoma Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oxidative Stress / Glucosephosphate Dehydrogenase / Glutamine / Melanoma Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article