An impressive response with larotrectinib in a patient with a papillary thyroid carcinoma harboring an SQSTM1-NTRK1 fusion.

Bargas, Sophie; Mc Leer, Anne; Mondet, Julie; Chabre, Olivier; Laramas, Mathieu

Bargas, Sophie; Mc Leer, Anne; Mondet, Julie; Chabre, Olivier; Laramas, Mathieu.

Affiliation

Bargas S; Grenoble Alpes University, Grenoble, France.
Mc Leer A; Medical Oncology, Cancer and Blood Diseases Department, Grenoble Alpes University Hospital, Grenoble, France.
Mondet J; Grenoble Alpes University, Grenoble, France.
Chabre O; Pathology Service, Molecular Pathology Unit, Grenoble Alpes University Hospital, Grenoble, France.
Laramas M; UGA/INSERM U1209/CNRS 5309, Institute for Advanced Biosciences, Grenoble Alpes University, Grenoble, France.

Eur J Endocrinol ; 186(4): K5-K8, 2022 Feb 23.

Article in En | MEDLINE | ID: mdl-35118995

Subject(s)

Pyrazoles/therapeutic use; Pyrimidines/therapeutic use; Receptor, trkA/genetics; Sequestosome-1 Protein/genetics; Thyroid Cancer, Papillary/diagnostic imaging; Thyroid Cancer, Papillary/genetics; Thyroid Neoplasms/genetics; Female; Gene Fusion/genetics; Humans; Middle Aged; Thyroid Cancer, Papillary/drug therapy; Thyroid Neoplasms/diagnostic imaging; Thyroid Neoplasms/drug therapy; Treatment Outcome

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrazoles / Pyrimidines / Thyroid Neoplasms / Receptor, trkA / Sequestosome-1 Protein / Thyroid Cancer, Papillary Limits: Female / Humans / Middle aged Language: En Journal: Eur J Endocrinol Journal subject: ENDOCRINOLOGIA Year: 2022 Type: Article Affiliation country: France

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