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A neuropathy-associated kinesin KIF1A mutation hyper-stabilizes the motor-neck interaction during the ATPase cycle.
Morikawa, Manatsu; Jerath, Nivedita U; Ogawa, Tadayuki; Morikawa, Momo; Tanaka, Yosuke; Shy, Michael E; Zuchner, Stephan; Hirokawa, Nobutaka.
Affiliation
  • Morikawa M; Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Jerath NU; Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, IA, USA.
  • Ogawa T; Neuromuscular Division, AdventHealth Orlando, Winter Park, FL, USA.
  • Morikawa M; Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Tanaka Y; Research Center for Advanced Medical Science, Dokkyo Medical University, Mibu, Japan.
  • Shy ME; Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
  • Zuchner S; Department of Anatomy and Neuroscience, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
  • Hirokawa N; Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
EMBO J ; 41(5): e108899, 2022 03 01.
Article in En | MEDLINE | ID: mdl-35132656
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kinesins / Adenosine Triphosphatases / Mutation / Neurons Type of study: Risk_factors_studies Limits: Aged / Humans / Male / Middle aged Language: En Journal: EMBO J Year: 2022 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kinesins / Adenosine Triphosphatases / Mutation / Neurons Type of study: Risk_factors_studies Limits: Aged / Humans / Male / Middle aged Language: En Journal: EMBO J Year: 2022 Type: Article Affiliation country: Japan