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Drosophila carrying epilepsy-associated variants in the vitamin B6 metabolism gene PNPO display allele- and diet-dependent phenotypes.
Chi, Wanhao; Iyengar, Atulya S R; Fu, Wenqin; Liu, Wei; Berg, Abigayle E; Wu, Chun-Fang; Zhuang, Xiaoxi.
Affiliation
  • Chi W; Committee on Genetics, Genomics and Systems Biology, University of Chicago, Chicago, IL 60637.
  • Iyengar ASR; Department of Neurobiology, University of Chicago, Chicago, IL 60637.
  • Fu W; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242.
  • Liu W; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242.
  • Berg AE; Department of Neurobiology, University of Chicago, Chicago, IL 60637.
  • Wu CF; Department of Environmental Health, School of Public Health, China Medical University, Shenyang 110122, China.
  • Zhuang X; Department of Biology, College of Liberal Arts and Sciences, University of Iowa, Iowa City, IA 52242.
Proc Natl Acad Sci U S A ; 119(9)2022 03 01.
Article in En | MEDLINE | ID: mdl-35217610
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Pyridoxaminephosphate Oxidase / Vitamin B 6 / Diet / Alleles / Epilepsy Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenotype / Pyridoxaminephosphate Oxidase / Vitamin B 6 / Diet / Alleles / Epilepsy Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2022 Type: Article