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ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation.
Kim, Hyun-Jung; Kim, Woo-Jin; Shin, Hye-Rim; Yoon, Hee-In; Moon, Jae-I; Lee, Eunji; Lim, Jin-Muk; Cho, Young-Dan; Lee, Mi-Hye; Kim, Hong-Gee; Ryoo, Hyun-Mo.
Affiliation
  • Kim HJ; Department of Molecular Genetics & Dental Pharmacology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Kim WJ; Department of Molecular Genetics & Dental Pharmacology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Shin HR; Department of Molecular Genetics & Dental Pharmacology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Yoon HI; Department of Molecular Genetics & Dental Pharmacology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Moon JI; Department of Molecular Genetics & Dental Pharmacology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Lee E; Department of Molecular Genetics & Dental Pharmacology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Lim JM; Biomedical Knowledge Engineering Laboratory, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Cho YD; Alopax-Algo, Co. Ltd, Seoul, South Korea.
  • Lee MH; Department of Periodontology, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
  • Kim HG; Department of Biology and Center for Cell Reprogramming, Georgetown University, Washington, DC, USA.
  • Ryoo HM; Biomedical Knowledge Engineering Laboratory, School of Dentistry and Dental Research Institute, Seoul National University, Seoul, South Korea.
Cell Mol Life Sci ; 79(3): 155, 2022 Feb 26.
Article in En | MEDLINE | ID: mdl-35218410
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Cellular Senescence / Chemokines, CC / Protein-Arginine Deiminase Type 2 / Hydrogen Peroxide Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: South Korea
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Cellular Senescence / Chemokines, CC / Protein-Arginine Deiminase Type 2 / Hydrogen Peroxide Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Mol Life Sci Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: South Korea