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Targeted A-to-G base editing in human mitochondrial DNA with programmable deaminases.
Cho, Sung-Ik; Lee, Seonghyun; Mok, Young Geun; Lim, Kayeong; Lee, Jaesuk; Lee, Ji Min; Chung, Eugene; Kim, Jin-Soo.
Affiliation
  • Cho SI; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea; Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.
  • Lee S; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea.
  • Mok YG; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea.
  • Lim K; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea.
  • Lee J; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea; Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.
  • Lee JM; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea; Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.
  • Chung E; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea; Department of Chemistry, Seoul National University, Seoul 08826, Republic of Korea.
  • Kim JS; Center for Genome Engineering, Institute for Basic Science, Daejeon 34126, Republic of Korea. Electronic address: jskim01@snu.ac.kr.
Cell ; 185(10): 1764-1776.e12, 2022 05 12.
Article in En | MEDLINE | ID: mdl-35472302
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / Mitochondrial Diseases Limits: Animals / Humans Language: En Journal: Cell Year: 2022 Type: Article
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA, Mitochondrial / Mitochondrial Diseases Limits: Animals / Humans Language: En Journal: Cell Year: 2022 Type: Article