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Convergent evolution of a parasite-encoded complement control protein-scaffold to mimic binding of mammalian TGF-ß to its receptors, TßRI and TßRII.
Mukundan, Ananya; Byeon, Chang-Hyeock; Hinck, Cynthia S; Cunningham, Kyle; Campion, Tiffany; Smyth, Danielle J; Maizels, Rick M; Hinck, Andrew P.
Affiliation
  • Mukundan A; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania USA.
  • Byeon CH; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania USA.
  • Hinck CS; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania USA.
  • Cunningham K; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
  • Campion T; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
  • Smyth DJ; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
  • Maizels RM; Wellcome Centre for Integrative Parasitology, Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom.
  • Hinck AP; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania USA. Electronic address: ahinck@pitt.edu.
J Biol Chem ; 298(6): 101994, 2022 06.
Article in En | MEDLINE | ID: mdl-35500648
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nematospiroides dubius / Helminth Proteins / Transforming Growth Factor beta / Receptors, Transforming Growth Factor beta / Host-Pathogen Interactions Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2022 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nematospiroides dubius / Helminth Proteins / Transforming Growth Factor beta / Receptors, Transforming Growth Factor beta / Host-Pathogen Interactions Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2022 Type: Article