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Cross-tissue immune cell analysis reveals tissue-specific features in humans.
Domínguez Conde, C; Xu, C; Jarvis, L B; Rainbow, D B; Wells, S B; Gomes, T; Howlett, S K; Suchanek, O; Polanski, K; King, H W; Mamanova, L; Huang, N; Szabo, P A; Richardson, L; Bolt, L; Fasouli, E S; Mahbubani, K T; Prete, M; Tuck, L; Richoz, N; Tuong, Z K; Campos, L; Mousa, H S; Needham, E J; Pritchard, S; Li, T; Elmentaite, R; Park, J; Rahmani, E; Chen, D; Menon, D K; Bayraktar, O A; James, L K; Meyer, K B; Yosef, N; Clatworthy, M R; Sims, P A; Farber, D L; Saeb-Parsy, K; Jones, J L; Teichmann, S A.
Affiliation
  • Domínguez Conde C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Xu C; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Jarvis LB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Rainbow DB; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Wells SB; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Gomes T; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Howlett SK; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Suchanek O; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Polanski K; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • King HW; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK.
  • Mamanova L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Huang N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Szabo PA; Department of Microbiology and Immunology, Columbia University Irving Medical Center, New York, NY, USA.
  • Richardson L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Bolt L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Fasouli ES; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Mahbubani KT; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Prete M; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Tuck L; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Richoz N; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Tuong ZK; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Campos L; Molecular Immunity Unit, Department of Medicine, University of Cambridge, Cambridge, UK.
  • Mousa HS; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Needham EJ; West Suffolk Hospital NHS Trust, Bury Saint Edmunds, UK.
  • Pritchard S; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Li T; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
  • Elmentaite R; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Park J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Rahmani E; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Chen D; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Menon DK; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.
  • Bayraktar OA; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, USA.
  • James LK; Department of Systems Biology, Columbia University Irving Medical Center, New York, NY, USA.
  • Meyer KB; Department of Anaesthesia, University of Cambridge, Cambridge, UK.
  • Yosef N; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Clatworthy MR; Centre for Immunobiology, Blizard Institute, Queen Mary University of London, London, UK.
  • Sims PA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK.
  • Farber DL; Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA.
  • Saeb-Parsy K; Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, Berkeley, CA, USA.
  • Jones JL; Chan Zuckerberg Biohub, San Francisco, CA, USA.
  • Teichmann SA; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
Science ; 376(6594): eabl5197, 2022 05 13.
Article in En | MEDLINE | ID: mdl-35549406
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / T-Lymphocytes / Sequence Analysis, RNA / Single-Cell Analysis / Transcriptome / Machine Learning Limits: Humans Language: En Journal: Science Year: 2022 Type: Article Affiliation country: United kingdom
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / T-Lymphocytes / Sequence Analysis, RNA / Single-Cell Analysis / Transcriptome / Machine Learning Limits: Humans Language: En Journal: Science Year: 2022 Type: Article Affiliation country: United kingdom