Generation of FLAG-tagged Arx knock-in mouse model.

Lim, Youngshin; Cho, Il-Taeg; Golden, Jeffrey A; Cho, Ginam

Lim, Youngshin; Cho, Il-Taeg; Golden, Jeffrey A; Cho, Ginam.

Affiliation

Lim Y; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Cho IT; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Golden JA; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Cho G; Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Genesis ; 60(6-7): e23479, 2022 07.

Article in En | MEDLINE | ID: mdl-35656878

Subject(s)

Autism Spectrum Disorder; Intellectual Disability; Animals; Autism Spectrum Disorder/genetics; Disease Models, Animal; Genes, Homeobox; Homeodomain Proteins/genetics; Homeodomain Proteins/metabolism; Intellectual Disability/genetics; Mice; Mutation; Transcription Factors/genetics

Key words

ARX; CRSPR/cas9; Flag-Arx knock-in mouse; brain development; detection of FLAG tagged-endogenous protein

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autism Spectrum Disorder / Intellectual Disability Type of study: Prognostic_studies Limits: Animals Language: En Journal: Genesis Journal subject: BIOLOGIA MOLECULAR Year: 2022 Type: Article Affiliation country: United States

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