How does flecainide impact RyR2 channel function?

Salvage, Samantha C; Huang, Christopher L-H; Fraser, James A; Dulhunty, Angela F

Salvage, Samantha C; Huang, Christopher L-H; Fraser, James A; Dulhunty, Angela F.

Affiliation

Salvage SC; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Huang CL; Department of Biochemistry, University of Cambridge, Cambridge, UK.
Fraser JA; Physiological Laboratory, University of Cambridge, Cambridge, UK.
Dulhunty AF; Physiological Laboratory, University of Cambridge, Cambridge, UK.

J Gen Physiol ; 154(9)2022 09 05.

Article in En | MEDLINE | ID: mdl-35713932

Subject(s)

Flecainide; Tachycardia, Ventricular; Anti-Arrhythmia Agents/pharmacology; Calcium/metabolism; Flecainide/metabolism; Flecainide/pharmacology; Humans; Myocytes, Cardiac/metabolism; Ryanodine/metabolism; Ryanodine/pharmacology; Ryanodine Receptor Calcium Release Channel/metabolism; Sodium/metabolism; Tachycardia, Ventricular/genetics; Tachycardia, Ventricular/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flecainide / Tachycardia, Ventricular Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Gen Physiol Year: 2022 Type: Article Affiliation country: United kingdom

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