Trastuzumab and Doxorubicin Sequential Administration Increases Oxidative Stress and Phosphorylation of Connexin 43 on Ser368.

Pecoraro, Michela; Marzocco, Stefania; Franceschelli, Silvia; Popolo, Ada

Pecoraro, Michela; Marzocco, Stefania; Franceschelli, Silvia; Popolo, Ada.

Affiliation

Pecoraro M; Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Marzocco S; Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Franceschelli S; Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy.
Popolo A; Department of Pharmacy, University of Salerno, 84084 Fisciano, Italy.

Int J Mol Sci ; 23(12)2022 Jun 07.

Article in En | MEDLINE | ID: mdl-35742818

Subject(s)

Breast Neoplasms; Connexin 43; Breast Neoplasms/metabolism; Cardiotoxicity/drug therapy; Cardiotoxicity/etiology; Connexin 43/metabolism; Doxorubicin/adverse effects; Female; Humans; Oxidative Stress; Phosphorylation; Receptor, ErbB-2/metabolism; Trastuzumab/adverse effects

Key words

Connexin 43; Doxorubicin; Trastuzumab; calcium homeostasis; cardiotoxicity

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Connexin 43 Type of study: Etiology_studies / Prognostic_studies Limits: Female / Humans Language: En Journal: Int J Mol Sci Year: 2022 Type: Article Affiliation country: Italy

Fulltext

XML

PubMed Links

Search on Google