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High-level dolutegravir resistance can emerge rapidly from few variants and spread by recombination: implications for integrase strand transfer inhibitor salvage therapy.
Huik, Kristi; Hill, Shawn; George, Jomy; Pau, Alice; Kuriakose, Safia; Lange, Camille M; Dee, Nicola; Stoll, Pamela; Khan, Muhammad; Rehman, Tauseef; Rehm, Catherine A; Dewar, Robin; Grossman, Zehava; Maldarelli, Frank.
Affiliation
  • Huik K; National Cancer Institute, Frederick.
  • Hill S; National Cancer Institute, Frederick.
  • George J; National Institutes of Health (NIH) Clinical, Center (CC).
  • Pau A; National Institute of Allergy and Infectious Diseases, Bethesda.
  • Kuriakose S; Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., NCI Campus at Frederick, Frederick, MD, USA.
  • Lange CM; National Cancer Institute, Frederick.
  • Dee N; Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., NCI Campus at Frederick, Frederick, MD, USA.
  • Stoll P; National Institutes of Health (NIH) Clinical, Center (CC).
  • Khan M; Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., NCI Campus at Frederick, Frederick, MD, USA.
  • Rehman T; Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., NCI Campus at Frederick, Frederick, MD, USA.
  • Rehm CA; National Institute of Allergy and Infectious Diseases, Bethesda.
  • Dewar R; Clinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., NCI Campus at Frederick, Frederick, MD, USA.
  • Grossman Z; National Cancer Institute, Frederick.
  • Maldarelli F; School of Public Health, Tel Aviv University, Tel Aviv, Israel.
AIDS ; 36(13): 1835-1840, 2022 11 01.
Article in En | MEDLINE | ID: mdl-35848510
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Quinolones / HIV Integrase Inhibitors / HIV Integrase Limits: Humans Language: En Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2022 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Quinolones / HIV Integrase Inhibitors / HIV Integrase Limits: Humans Language: En Journal: AIDS Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 2022 Type: Article