Endothelial Cell Infection by Guinea Pig Cytomegalovirus Is a Lytic or Persistent Infection Depending on Tissue Origin but Requires Viral Pentamer Complex and pp65 Tegument Protein.

Choi, K Yeon; El-Hamdi, Nadia; McGregor, Alistair

Choi, K Yeon; El-Hamdi, Nadia; McGregor, Alistair.

Affiliation

Choi KY; Department of Microbial Pathogenesis & Immunology, Health Science Center, School of Medicine, Texas A&M University, Bryan, Texas, USA.
El-Hamdi N; Department of Microbial Pathogenesis & Immunology, Health Science Center, School of Medicine, Texas A&M University, Bryan, Texas, USA.
McGregor A; Department of Microbial Pathogenesis & Immunology, Health Science Center, School of Medicine, Texas A&M University, Bryan, Texas, USA.

J Virol ; 96(17): e0083122, 2022 09 14.

Article in En | MEDLINE | ID: mdl-36000848

Subject(s)

Cytomegalovirus Infections/virology; Endothelial Cells/virology; Roseolovirus; Animals; Antibodies, Neutralizing; Cell Line; Disease Models, Animal; Endothelial Cells/metabolism; Female; Guinea Pigs; Humans; Infant, Newborn; Persistent Infection; Placenta; Pregnancy; Viral Envelope Proteins/metabolism

Key words

CMV vaccine; congenital CMV; cytomegalovirus; endothelial cells; gB glycoprotein; guinea pig; neutralizing antibodies; pentamer complex; umbilical cord vein endothelial cell; virus tropism

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytomegalovirus Infections / Roseolovirus / Endothelial Cells Type of study: Prognostic_studies Limits: Animals / Female / Humans / Newborn / Pregnancy Language: En Journal: J Virol Year: 2022 Type: Article Affiliation country: United States

Fulltext

XML

PubMed Links

Search on Google