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The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron.
Ichikawa, Saki; Flaxman, Hope A; Xu, Wenqing; Vallavoju, Nandini; Lloyd, Hannah C; Wang, Binyou; Shen, Dacheng; Pratt, Matthew R; Woo, Christina M.
Affiliation
  • Ichikawa S; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Flaxman HA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Xu W; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Vallavoju N; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Lloyd HC; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Wang B; Department of Chemistry, University of Southern California, Los Angeles, CA, USA.
  • Shen D; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Pratt MR; Department of Chemistry, University of Southern California, Los Angeles, CA, USA.
  • Woo CM; Department of Biological Sciences, University of Southern California, Los Angeles, CA, USA.
Nature ; 610(7933): 775-782, 2022 10.
Article in En | MEDLINE | ID: mdl-36261529
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligase Complexes / Proteolysis / Imides Limits: Humans Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligase Complexes / Proteolysis / Imides Limits: Humans Language: En Journal: Nature Year: 2022 Type: Article Affiliation country: United States