Efficacy and Safety of a Drug-Free, Barrier-Forming Nasal Spray for Allergic Rhinitis: Randomized, Open-Label, Crossover Noninferiority Trial.

Nehrig, Julian; Grosse, Nicole; Hohenfeld, Ilja P; Hohlfeld, Jens M; Badorrek, Philipp

Nehrig, Julian; Grosse, Nicole; Hohenfeld, Ilja P; Hohlfeld, Jens M; Badorrek, Philipp.

Affiliation

Nehrig J; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany.
Grosse N; Altamira Medica AG, Zug, Switzerland.
Hohenfeld IP; Altamira Medica AG, Zug, Switzerland.
Hohlfeld JM; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Hannover, Germany.
Badorrek P; Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

Int Arch Allergy Immunol ; 184(2): 111-121, 2023.

Article in En | MEDLINE | ID: mdl-36323243

Subject(s)

Rhinitis, Allergic, Seasonal; Rhinitis, Allergic; Adult; Humans; Nasal Sprays; Rhinitis, Allergic, Seasonal/drug therapy; Rhinitis, Allergic, Seasonal/prevention & control; Allergens/therapeutic use; Nasal Mucosa; Double-Blind Method; Administration, Intranasal

Key words

Allergen challenge chamber; Allergy; Bentonite; Dactylis glomerata; Hydroxypropyl methylcellulose; Medical device; Nasal spray; Pollen; Rhinorrhea; Thixotropy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhinitis, Allergic, Seasonal / Rhinitis, Allergic Type of study: Clinical_trials Limits: Adult / Humans Language: En Journal: Int Arch Allergy Immunol Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Type: Article Affiliation country: Germany

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