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Loss of Brca1 and Trp53 in adult mouse mammary ductal epithelium results in development of hormone receptor-positive or hormone receptor-negative tumors, depending on inactivation of Rb family proteins.
Szabova, Ludmila; Gordon, Melanie B; Lu, Lucy; Pate, Nathan; Bassel, Laura; Iacovelli, Anthony J; Karim, Baktiar; Homan, Philip J; Householder, Deborah B; Guerin, Theresa M; Burkett, Sandra; Day, Amanda M; Custer, Wendi; Weaver Ohler, Zoe.
Affiliation
  • Szabova L; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA. lszabova@mail.nih.gov.
  • Gordon MB; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Lu L; Center for Advanced Preclinical Research, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
  • Pate N; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Bassel L; Sanofi,Global Discovery Pathology, Translational In Vivo Models Platform, Framingham, MA, USA.
  • Iacovelli AJ; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Karim B; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Homan PJ; Genentech, Inc., South San Francisco, CA, USA.
  • Householder DB; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Guerin TM; Molecular Histopathology Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Burkett S; CCR Collaborative Bioinformatics Resource, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
  • Day AM; Center for Advanced Preclinical Research, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
  • Custer W; Center for Advanced Preclinical Research, Frederick National Laboratory for Cancer Research, National Cancer Institute, Frederick, MD, USA.
  • Weaver Ohler Z; Molecular Cytogenetics Core Facility, Mouse Cancer Genetics Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD, USA.
Breast Cancer Res ; 24(1): 75, 2022 11 04.
Article in En | MEDLINE | ID: mdl-36333737
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Mammary Neoplasms, Animal / Mammary Glands, Human Limits: Animals / Female / Humans Language: En Journal: Breast Cancer Res Journal subject: NEOPLASIAS Year: 2022 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Mammary Neoplasms, Animal / Mammary Glands, Human Limits: Animals / Female / Humans Language: En Journal: Breast Cancer Res Journal subject: NEOPLASIAS Year: 2022 Type: Article Affiliation country: United States