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Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes.
Fan, Chengcheng; Cohen, Alexander A; Park, Miso; Hung, Alfur Fu-Hsin; Keeffe, Jennifer R; Gnanapragasam, Priyanthi N P; Lee, Yu E; Gao, Han; Kakutani, Leesa M; Wu, Ziyan; Kleanthous, Harry; Malecek, Kathryn E; Williams, John C; Bjorkman, Pamela J.
Affiliation
  • Fan C; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Cohen AA; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Park M; Department of Molecular Medicine, City of Hope, Duarte, CA 91010, USA.
  • Hung AF; Department of Molecular Medicine, City of Hope, Duarte, CA 91010, USA.
  • Keeffe JR; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Gnanapragasam PNP; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Lee YE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Gao H; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Kakutani LM; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Wu Z; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Kleanthous H; Bill and Melinda Gates Foundation, Seattle, WA 98109, USA.
  • Malecek KE; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA.
  • Williams JC; Department of Molecular Medicine, City of Hope, Duarte, CA 91010, USA.
  • Bjorkman PJ; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: bjorkman@caltech.edu.
Immunity ; 55(12): 2419-2435.e10, 2022 12 13.
Article in En | MEDLINE | ID: mdl-36370711

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Severe acute respiratory syndrome-related coronavirus / Nanoparticles / COVID-19 Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Severe acute respiratory syndrome-related coronavirus / Nanoparticles / COVID-19 Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2022 Type: Article Affiliation country: United States