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Discovery of pan-IAP degraders via a CRBN recruiting mechanism.
Park, Seulki; Kim, Dayoung; Lee, Woori; Cho, Jin Hwa; Kim, Sungyoung; Lee, Ga Seul; Moon, Jeong Hee; Kim, Jung-Ae; Ha, Jae Du; Kim, Jeong-Hoon; Kim, Hyun Jin.
Affiliation
  • Park S; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea.
  • Kim D; Data Convergence Drug Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea.
  • Lee W; Data Convergence Drug Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea; Department of New Drug Discovery and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, South Korea.
  • Cho JH; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea.
  • Kim S; Critical Diseases Diagnostics Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea; Department of Proteome Structural Biology, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon, 34113, South Korea.
  • Lee GS; Core Research Facility & Analysis Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea; College of Pharmacy, Chungbuk National University, Cheongju, Chungbuk, 28160, South Korea.
  • Moon JH; Core Research Facility & Analysis Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea.
  • Kim JA; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea; Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon, 34113, South Korea; Aging Convergence Research Ce
  • Ha JD; Data Convergence Drug Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea.
  • Kim JH; Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology KRIBB, Daejeon, 34141, South Korea; Department of New Drug Discovery and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, South Korea; Department of Functional Gen
  • Kim HJ; Data Convergence Drug Research Center, Therapeutics and Biotechnology Division, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea; Department of New Drug Discovery and Development, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon, 305-764, South Korea. Elect
Eur J Med Chem ; 245(Pt 2): 114910, 2023 Jan 05.
Article in En | MEDLINE | ID: mdl-36410083
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Apoptosis Language: En Journal: Eur J Med Chem Year: 2023 Type: Article Affiliation country: South Korea
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Apoptosis Language: En Journal: Eur J Med Chem Year: 2023 Type: Article Affiliation country: South Korea