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The dynamic clustering of insulin receptor underlies its signaling and is disrupted in insulin resistance.
Dall'Agnese, Alessandra; Platt, Jesse M; Zheng, Ming M; Friesen, Max; Dall'Agnese, Giuseppe; Blaise, Alyssa M; Spinelli, Jessica B; Henninger, Jonathan E; Tevonian, Erin N; Hannett, Nancy M; Lazaris, Charalampos; Drescher, Hannah K; Bartsch, Lea M; Kilgore, Henry R; Jaenisch, Rudolf; Griffith, Linda G; Cisse, Ibrahim I; Jeppesen, Jacob F; Lee, Tong I; Young, Richard A.
Affiliation
  • Dall'Agnese A; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Platt JM; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Zheng MM; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Friesen M; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Dall'Agnese G; Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Blaise AM; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Spinelli JB; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Henninger JE; Department of Medicine, University of Udine, Udine, 33100, Italy.
  • Tevonian EN; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Hannett NM; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Lazaris C; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Drescher HK; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Bartsch LM; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Kilgore HR; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Jaenisch R; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Griffith LG; Division of Gastroenterology, Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Cisse II; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Jeppesen JF; Whitehead Institute for Biomedical Research, Cambridge, MA, 02142, USA.
  • Lee TI; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Young RA; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
Nat Commun ; 13(1): 7522, 2022 12 06.
Article in En | MEDLINE | ID: mdl-36473871
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Diabetes Mellitus, Type 2 Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Diabetes Mellitus, Type 2 Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2022 Type: Article Affiliation country: United States