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Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion.
Aliakbarinodehi, Nima; Gallud, Audrey; Mapar, Mokhtar; Wesén, Emelie; Heydari, Sahar; Jing, Yujia; Emilsson, Gustav; Liu, Kai; Sabirsh, Alan; Zhdanov, Vladimir P; Lindfors, Lennart; Esbjörner, Elin K; Höök, Fredrik.
Affiliation
  • Aliakbarinodehi N; Division of Nano and Biophysics, Department of Physics, Chalmers University of Technology 41296 Göteborg, Sweden.
  • Gallud A; Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Göteborg, Sweden.
  • Mapar M; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden.
  • Wesén E; Division of Nano and Biophysics, Department of Physics, Chalmers University of Technology 41296 Göteborg, Sweden.
  • Heydari S; Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Göteborg, Sweden.
  • Jing Y; Division of Chemical Biology, Department of Biology and Biological Engineering, Chalmers University of Technology, 41296 Göteborg, Sweden.
  • Emilsson G; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden.
  • Liu K; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden.
  • Sabirsh A; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden.
  • Zhdanov VP; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden.
  • Lindfors L; Division of Nano and Biophysics, Department of Physics, Chalmers University of Technology 41296 Göteborg, Sweden.
  • Esbjörner EK; Boreskov Institute of Catalysis, Russian Academy of Sciences, Novosibirsk 630090, Russia.
  • Höök F; Advanced Drug Delivery, Pharmaceutical Sciences, R&D, AstraZeneca, 43181 Gothenburg, Sweden.
ACS Nano ; 16(12): 20163-20173, 2022 12 27.
Article in En | MEDLINE | ID: mdl-36511601
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nanoparticles / Protein Corona Language: En Journal: ACS Nano Year: 2022 Type: Article Affiliation country: Sweden
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nanoparticles / Protein Corona Language: En Journal: ACS Nano Year: 2022 Type: Article Affiliation country: Sweden