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Natural variation in the binding pocket of a parasitic flatworm TRPM channel resolves the basis for praziquantel sensitivity.
Rohr, Claudia M; Sprague, Daniel J; Park, Sang-Kyu; Malcolm, Nicholas J; Marchant, Jonathan S.
Affiliation
  • Rohr CM; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226.
  • Sprague DJ; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226.
  • Park SK; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226.
  • Malcolm NJ; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226.
  • Marchant JS; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI 53226.
Proc Natl Acad Sci U S A ; 120(1): e2217732120, 2023 01 03.
Article in En | MEDLINE | ID: mdl-36574686
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platyhelminths / Trematoda / Cestoda / TRPM Cation Channels Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Platyhelminths / Trematoda / Cestoda / TRPM Cation Channels Type of study: Diagnostic_studies Limits: Animals Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article