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Characterization and implications of host-cell protein aggregates in biopharmaceutical processing.
Oh, Young Hoon; Becker, Matthew L; Mendola, Kerri M; Choe, Leila H; Min, Lie; Lee, Kelvin H; Yigzaw, Yinges; Seay, Alexander; Bill, Jerome; Li, Xuanwen; Roush, David J; Cramer, Steven M; Menegatti, Stefano; Lenhoff, Abraham M.
Affiliation
  • Oh YH; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
  • Becker ML; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
  • Mendola KM; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
  • Choe LH; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
  • Min L; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
  • Lee KH; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
  • Yigzaw Y; Purification Process Development, Genentech, Inc., South San Francisco, California, USA.
  • Seay A; Purification Process Development, Genentech, Inc., South San Francisco, California, USA.
  • Bill J; Purification Process Development, Genentech, Inc., South San Francisco, California, USA.
  • Li X; Analytical Research and Development, Merck & Co., Inc., Kenilworth, New Jersey, USA.
  • Roush DJ; Process Research and Development, Merck & Co., Inc., Rahway, New Jersey, USA.
  • Cramer SM; Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York, USA.
  • Menegatti S; Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina, USA.
  • Lenhoff AM; Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware, USA.
Biotechnol Bioeng ; 120(4): 1068-1080, 2023 04.
Article in En | MEDLINE | ID: mdl-36585356
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Protein Aggregates Limits: Animals / Humans Language: En Journal: Biotechnol Bioeng Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Biological Products / Protein Aggregates Limits: Animals / Humans Language: En Journal: Biotechnol Bioeng Year: 2023 Type: Article Affiliation country: United States