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Two new alkaloids from Dendrobium nobile Lindl. exhibited neuroprotective activity, and dendrobine alleviated Aß1-42 -induced apoptosis by inhibiting CDK5 activation in PC12 cells.
Zhang, Cheng-Chen; Kong, Yan-Li; Zhang, Mao-Sheng; Wu, Qin; Shi, Jing-Shan.
Affiliation
  • Zhang CC; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, School of Pharmacy, Zunyi Medical University, Zunyi, China.
  • Kong YL; State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medcial University, Guiyang, China.
  • Zhang MS; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, School of Pharmacy, Zunyi Medical University, Zunyi, China.
  • Wu Q; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, School of Pharmacy, Zunyi Medical University, Zunyi, China.
  • Shi JS; Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, School of Pharmacy, Zunyi Medical University, Zunyi, China.
Drug Dev Res ; 84(2): 262-274, 2023 04.
Article in En | MEDLINE | ID: mdl-36658700
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendrobium / Alkaloids Limits: Animals Language: En Journal: Drug Dev Res Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dendrobium / Alkaloids Limits: Animals Language: En Journal: Drug Dev Res Year: 2023 Type: Article Affiliation country: China