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Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening.
Hayat, Ateequllah; Carter, Edward P; King, Hamish W; Ors, Aysegul; Doe, Aaron; Teijeiro, Saul A; Charrot, Sarah; Godinho, Susana; Cutillas, Pedro; Mohammed, Hisham; Grose, Richard P; Ficz, Gabriella.
Affiliation
  • Hayat A; Institute of Medical and Biomedical Education, St George's, University of London, Cranmer Terrace, Tooting, London SW17 0RE, UK.
  • Carter EP; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • King HW; Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Ors A; Epigenetics and Development Division, Walter and Eliza Hall Institute of Medical Research, Royal Parade, Parkville, VIC 3052, Australia.
  • Doe A; Knight Cancer Institute, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239-3098, USA.
  • Teijeiro SA; Knight Cancer Institute, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239-3098, USA.
  • Charrot S; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Godinho S; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Cutillas P; Centre for Molecular Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Mohammed H; Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
  • Grose RP; Knight Cancer Institute, Oregon Health and Science University, 3181 S.W. Sam Jackson Park Road, Portland, OR 97239-3098, USA.
  • Ficz G; Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK.
Dis Model Mech ; 16(2)2023 02 01.
Article in En | MEDLINE | ID: mdl-36661191
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Receptor, ErbB-2 Limits: Humans Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2023 Type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromatin / Receptor, ErbB-2 Limits: Humans Language: En Journal: Dis Model Mech Journal subject: MEDICINA Year: 2023 Type: Article Affiliation country: United kingdom