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PGC-1α senses the CBC of pre-mRNA to dictate the fate of promoter-proximally paused RNAPII.
Rambout, Xavier; Cho, Hana; Blanc, Roméo; Lyu, Qing; Miano, Joseph M; Chakkalakal, Joe V; Nelson, Geoffrey M; Yalamanchili, Hari K; Adelman, Karen; Maquat, Lynne E.
Affiliation
  • Rambout X; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for RNA Biology, University of Rochester, Rochester, NY 14642, USA. Electronic address: xavier_rambout@urmc.rochester.edu.
  • Cho H; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for RNA Biology, University of Rochester, Rochester, NY 14642, USA.
  • Blanc R; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA.
  • Lyu Q; Department of Medicine, Aab Cardiovascular Research Institute, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA.
  • Miano JM; Department of Medicine, Aab Cardiovascular Research Institute, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA.
  • Chakkalakal JV; Department of Pharmacology and Physiology, University of Rochester Medical Center, Rochester, NY 14642, USA; Department of Biomedical Engineering, University of Rochester Medical Center, Rochester, NY 14642, USA.
  • Nelson GM; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Yalamanchili HK; Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.
  • Adelman K; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.
  • Maquat LE; Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA; Center for RNA Biology, University of Rochester, Rochester, NY 14642, USA. Electronic address: lynne_maquat@urmc.rochester.edu.
Mol Cell ; 83(2): 186-202.e11, 2023 Jan 19.
Article in En | MEDLINE | ID: mdl-36669479
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / RNA Precursors Limits: Animals Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Transcription Factors / RNA Precursors Limits: Animals Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article