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Telomerase inhibition is an effective therapeutic strategy in TERT promoter-mutant glioblastoma models with low tumor volume.
Aquilanti, Elisa; Kageler, Lauren; Watson, Jacqueline; Baird, Duncan M; Jones, Rhiannon E; Hodges, Marie; Szegletes, Zsofia M; Doench, John G; Strathdee, Craig A; Figueroa, Jose Ricardo Mc Faline; Ligon, Keith L; Beck, Matthew; Wen, Patrick Y; Meyerson, Matthew.
Affiliation
  • Aquilanti E; Division of Neuro Oncology, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
  • Kageler L; Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
  • Watson J; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Baird DM; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Jones RE; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Hodges M; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK.
  • Szegletes ZM; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK.
  • Doench JG; Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK.
  • Strathdee CA; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Figueroa JRMF; Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Ligon KL; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
  • Beck M; Division of Neuro Oncology, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
  • Wen PY; Department of Pathology, Brigham and Women's Hospital, Boston Children's Hospital, Dana Farber Cancer Institute, Boston, Massachusetts, USA.
  • Meyerson M; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Neuro Oncol ; 25(7): 1275-1285, 2023 07 06.
Article in En | MEDLINE | ID: mdl-36694348
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glioblastoma / Telomerase Limits: Humans Language: En Journal: Neuro Oncol Journal subject: NEOPLASIAS / NEUROLOGIA Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Glioblastoma / Telomerase Limits: Humans Language: En Journal: Neuro Oncol Journal subject: NEOPLASIAS / NEUROLOGIA Year: 2023 Type: Article Affiliation country: United States