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Targeted pseudouridylation: An approach for suppressing nonsense mutations in disease genes.
Adachi, Hironori; Pan, Yi; He, Xueyang; Chen, Jonathan L; Klein, Bart; Platenburg, Gerard; Morais, Pedro; Boutz, Paul; Yu, Yi-Tao.
Affiliation
  • Adachi H; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, USA.
  • Pan Y; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, USA.
  • He X; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, USA.
  • Chen JL; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, USA.
  • Klein B; ProQR Therapeutics, Leiden, the Netherlands.
  • Platenburg G; ProQR Therapeutics, Leiden, the Netherlands.
  • Morais P; ProQR Therapeutics, Leiden, the Netherlands. Electronic address: pmorais@proqr.com.
  • Boutz P; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, USA; Center for Biomedical Informatics and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: paul_boutz@urmc.rochester.edu.
  • Yu YT; Department of Biochemistry and Biophysics, Center for RNA Biology, University of Rochester Medical Center, Rochester, NY, USA. Electronic address: yitao_yu@urmc.rochester.edu.
Mol Cell ; 83(4): 637-651.e9, 2023 02 16.
Article in En | MEDLINE | ID: mdl-36764303
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Codon, Nonsense Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article Affiliation country: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Protein Biosynthesis / Codon, Nonsense Limits: Humans Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2023 Type: Article Affiliation country: United States