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A trans-kingdom T6SS effector induces the fragmentation of the mitochondrial network and activates innate immune receptor NLRX1 to promote infection.
Sá-Pessoa, Joana; López-Montesino, Sara; Przybyszewska, Kornelia; Rodríguez-Escudero, Isabel; Marshall, Helina; Ova, Adelia; Schroeder, Gunnar N; Barabas, Peter; Molina, María; Curtis, Tim; Cid, Víctor J; Bengoechea, José A.
Affiliation
  • Sá-Pessoa J; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • López-Montesino S; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid and Instituto Ramón y Cajal de Investigaciones Sanitarias, Madrid, Spain.
  • Przybyszewska K; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Rodríguez-Escudero I; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid and Instituto Ramón y Cajal de Investigaciones Sanitarias, Madrid, Spain.
  • Marshall H; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Ova A; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Schroeder GN; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Barabas P; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Molina M; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid and Instituto Ramón y Cajal de Investigaciones Sanitarias, Madrid, Spain.
  • Curtis T; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
  • Cid VJ; Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad Complutense de Madrid and Instituto Ramón y Cajal de Investigaciones Sanitarias, Madrid, Spain.
  • Bengoechea JA; Wellcome-Wolfson Institute for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK. j.bengoechea@qub.ac.uk.
Nat Commun ; 14(1): 871, 2023 02 16.
Article in En | MEDLINE | ID: mdl-36797302
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Cullin Proteins Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Cullin Proteins Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2023 Type: Article Affiliation country: United kingdom